Martijn Verdoes

Verdoes, Martijn 2017.jpg
Name:
Dr. Martijn Verdoes 


Function:
Assistant Professor


Theme:
Cancer development and immune defense



Profile

Research interests include organic chemistry, chemical biology and tumor immunology with the aim to combine all these disciplines in the new and emerging field of chemical immunology. Current research projects focus on the development of novel immunomodulatory approaches to aid cancer immunotherapy. Molecularly defined macromolecules are synthesized to deliver tumor antigens to dendritic cells to educate the immune system. Furthermore, molecules which are able to dampen the immunosuppression in the tumor microenvironment are designed and synthesized to prime a tumor for infiltrating effector immune cells. To study the role of proteases in cancer, in specific immune cells and in specific cellular compartments, smart imaging tools – activity-based probes – are designed and synthesized and applied in noninvasive optical imaging, intravital microscopy and biochemical characterization studies. Together, the research efforts at the interface of chemistry and immunology will give us new insights in the development of more effective and safer immunotherapeutic approaches. 

More information can be found on the homepage of his laboratory: www.verdoeslab.com.​


Secondary functions

None


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