Research within the Laboratory of Pediatric Oncology focuses on the cell biological and genetic characterization of childhood malignancies in order to improve diagnosis and treatment of these diseases. More specifically, we apply in vitro as well as in vivo experimental approaches to model genomic abnormalities in pediatric Acute Lymphoblastic Leukemia (ALL). A second line of research involves regulation of invasion and metastasis in solid tumors by the actomyosin cytoskeleton, which is part of an ongoing productive partnership with the Netherlands Cancer Institute (NKI-AVL).
Frank N. van Leeuwen is head of the laboratory of Pediatric Oncology and staff member within the Departments of Pediatrics and Laboratory Medicine.
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