Mechanobiology of cancer invasion and wound healing
Daphne Weihs, Biomedical Engineering, Technion-Israel, Institute of Technology, Haifa, Israel
Katarina Wolf, Dept. of Cell Biology, RIMLS
Our focus is on the mechanobiology of (1) invasive cancercells and (2) wound healing. Metastatic cells must change shape and apply forces to invade. Mechanobiology highlights differences of metastatic cells from benign, revealing mechanically invasive subpopulations. We also test the use of mechanobiologal approaches to accelerate wound healing, e.g. by mechanical stretching.
- Metastatic cancer cells tenaciously indent impenetrable, soft substrates, New J Phys 15, 035022, 2013
- Low-level stretching accelerates cell migration into a gap, Int Wound J, 2016
- Cell-gel mechanical interactions as an approach to rapidly and quantitatively reveal invasive subpopulations of metastatic cancer cells. Tissue Eng C, 2017
<< back to all events